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Cardiac Arrest in Pregnancy In-Hospital ACLS Algorithm - 2025 Guidelines Coming Soon

Bradycardia acls algorithm

Cardiac arrest during pregnancy is a rare but critical emergency. When it happens, healthcare providers must act fast. They need to manage two patients at once: the mother and the fetus. The standard Advanced Cardiovascular Life Support (ACLS) protocol needs adjustments to improve outcomes for both.

Understanding this modified approach is essential for any healthcare professional in an acute care setting. It involves specific techniques and considerations that address the unique physiological changes of pregnancy. Knowing these steps helps ensure the resuscitation team can provide the best possible care during a high-stakes emergency. This post will walk you through the key components of the algorithm, from manual uterine displacement to the timing of a perimortem cesarean delivery.

Understanding the Maternal ACLS Algorithm

When a pregnant patient goes into cardiac arrest, the standard ACLS guidelines are the foundation of care. However, the team must immediately implement maternal-specific modifications. The primary goal is to relieve the physiological burdens of pregnancy that can interfere with resuscitation.

The algorithm runs parallel to the standard ACLS sequence of chest compressions, airway management, and defibrillation. The key is to integrate maternal interventions without delaying standard lifesaving care. A designated team leader should assign roles quickly, ensuring one person is responsible for maternal-specific tasks while others manage the primary cardiac arrest response.

Priority Actions in Maternal Cardiac Arrest

The moment cardiac arrest is identified in a pregnant patient, the resuscitation team should initiate the following actions simultaneously with high-quality CPR:

  1. Activate the Obstetrical Emergency Response Team: This brings obstetricians, neonatologists, and specialized nurses to the scene immediately. Their expertise is crucial for managing the pregnancy-specific aspects of the event.
  2. Perform Manual Uterine Displacement (MUD): A gravid uterus (typically after 20 weeks of gestation) can compress the inferior vena cava and aorta. This compression, known as aortocaval compression, significantly reduces venous return to the heart and lowers cardiac output. MUD is the most important initial intervention. A team member should manually push the uterus to the patient’s left side to relieve this pressure.
  3. Establish Airway and Provide Oxygen: Pregnant patients have a higher oxygen demand and a lower functional residual capacity, making them prone to rapid desaturation. Secure the airway early and provide 100% oxygen.
  4. Gain IV Access Above the Diaphragm: Establish intravenous or intraosseous (IO) access in a vein in the arm or a central line. This ensures medications reach the central circulation without being impeded by aortocaval compression.

Key Modifications to Standard ACLS Protocols

While the core principles of ACLS remain, several adjustments are necessary to optimize the resuscitation of a pregnant patient. These changes account for the anatomical and physiological shifts that occur during pregnancy.

High-Quality CPR and Manual Uterine Displacement

Continuous, high-quality chest compressions are vital. For pregnant patients, compressions should be performed slightly higher on the sternum to account for the elevation of the diaphragm.

Throughout the resuscitation, Manual Uterine Displacement must be maintained. If MUD is not effective or feasible, the team can place the patient in a 30-degree left lateral tilt using a wedge or pillows. However, MUD is preferred because it allows the patient to remain supine, which makes high-quality chest compressions easier to perform.

Advanced Airway Management

Because of increased aspiration risk and potential difficulty with intubation, experienced personnel should manage the airway. A smaller endotracheal tube may be necessary due to airway edema. Continuous waveform capnography is essential to confirm tube placement and monitor CPR quality.

Defibrillation and Medications

The indications and energy doses for defibrillation are the same for pregnant patients as for non-pregnant patients. There is no evidence that defibrillation harms the fetus.

Similarly, standard ACLS drug protocols, including epinephrine and amiodarone, should be followed without modification. The priority is maternal survival, which offers the best chance for fetal survival.

The Role of Perimortem Cesarean Delivery (PMCD)

If the patient does not achieve Return of Spontaneous Circulation (ROSC) quickly, the team must prepare for a perimortem cesarean delivery. This procedure is also known as a resuscitative hysterotomy.

The goal of a PMCD is twofold:

  1. Improve Maternal Resuscitation: Delivering the fetus and placenta relieves aortocaval compression, which can dramatically increase venous return and improve the effectiveness of CPR. This can lead to maternal ROSC.
  2. Improve Fetal Outcome: If the fetus is viable, delivery provides a chance for neonatal resuscitation.

Timing the Four-Minute Rule

The decision to perform a PMCD should be made rapidly. The “four-minute rule” is a critical guideline: if there is no maternal ROSC within four minutes of the cardiac arrest, the team should begin the cesarean delivery. The goal is to deliver the baby by the fifth minute.

This timeline is crucial because the chances of both maternal and fetal survival decrease significantly as time passes. The delivery should occur at the site of the arrest, whether it’s in the emergency department, ICU, or operating room. Do not move the patient. The procedure must be performed while high-quality CPR and other ACLS interventions continue.

Common Causes of Maternal Cardiac Arrest (The H's and T's)

Identifying and treating the underlying cause of the arrest is a core part of the ACLS algorithm. For pregnant patients, the differential diagnosis includes the standard H’s and T’s, plus several causes specific to pregnancy.

Pregnancy-Specific Causes (BEAU-CHOPS mnemonic):

  • Bleeding/DIC
  • Embolism (coronary, pulmonary, or amniotic fluid)
  • Anesthetic Complications
  • Uterine Atony
  • Cardiac Disease (MI, Aortic Dissection, Cardiomyopathy)
  • Hypertension/Preeclampsia/Eclampsia
  • Other (standard H’s and T’s)
  • Placental Abruption/Previa
  • Sepsis

The resuscitation team should work through this list to identify a reversible cause while continuing resuscitation efforts.

Master the Maternal ACLS Algorithm with Us

The Cardiac Arrest in Pregnancy In-Hospital ACLS Algorithm requires a coordinated, multi-disciplinary team effort. Every member must understand their role and the unique modifications needed to save two lives. Regular training and simulation drills are the best way to ensure your team is prepared for this high-acuity, low-frequency event.

At Safety Training Seminars, we provide official American Heart Association (AHA) courses, including ACLS, BLS, and PALS, that equip healthcare professionals with these lifesaving skills. Our classes cover the latest guidelines and provide hands-on practice to build your confidence. With over 70 locations across California and a commitment to excellent customer service, we make it convenient to get the training you need. To sharpen your skills and ensure you’re ready to respond effectively, book an ACLS course with us today.